Platelet function (measured by Platelet Function Analyser - 100) and obstructive sleep apnoea

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Platelet function in patients with obstructive sleep apnoea syndrome.

Patients with obstructive sleep apnoea syndrome (OSAS) are subject to an increased cardiovascular morbidity including myocardial infarction and stroke. Platelets play an important role in the pathogenesis and triggering of acute cardiovascular syndromes. So far, the influence of OSAS on platelet function is not fully understood. Platelet aggregability to epinephrine, collagen, arachidonic acid,...

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Evaluation of a Platelet Function Analyser (PFA-100) in patients with a bleeding tendency.

OBJECTIVE To investigate pre-analytical variables and the diagnostic performance of the platelet function analyser (PFA-100), a new device to test primary haemostasis in vitro by simulating platelet adhesion and aggregation under high shear stress. METHODS Venous whole citrated blood is aspirated through a capillary towards an aperture of a collagen coated membrane containing either adenosine...

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BACKGROUND Closure time (CT), measured by platelet function analyzer (PFA-100) device, is now available to the clinical laboratory as a possible alternative or supplement to the bleeding time test. AIM On behalf of the Platelet Physiology Subcommittee of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis (ISTH-SSC), a working Group was form...

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ژورنال

عنوان ژورنال: Journal of Sleep Research

سال: 2005

ISSN: 0962-1105,1365-2869

DOI: 10.1111/j.1365-2869.2005.00469.x